Combining tricyclic antidepressants like amitriptyline with antihistamines like Benadryl can cause dangerous anticholinergic overload, increasing risks of confusion, delirium, and dementia - especially in older adults. Learn how to spot and avoid this hidden drug interaction.
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Therapeutic drug monitoring for tricyclic antidepressants prevents deadly toxicity by tracking blood levels, identifying genetic risks, and catching early signs of heart damage before it’s too late.
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